I know what crossfire run only in fullscreen. This is my case.

Log file:


23:10:57:547 (00010804) > [Startup] Rise of the Tomb Raider
23:10:57:547 (00010804) > [Startup] ==============
23:10:57:547 (00010804) > [Startup]
23:10:57:547 (00010804) > [Startup] Build: v1.0 build 616.5_64
23:10:57:547 (00010804) > [Startup] Windows 10 Pro (build 10240)
23:10:57:547 (00010804) > [Startup] Game directory: F:\\Rise of the Tomb Raider\
23:10:57:547 (00010804) > [Startup]
23:10:57:547 (00010804) > [Startup] Memory statistics:
23:10:57:547 (00010804) > [Startup] Total RAM = 8.0 GB (8175 MB)
23:10:57:547 (00010804) > [Startup] Avail RAM = 6.4 GB (6522 MB)
23:10:57:547 (00010804) > [Startup] Total virtual memory = 131072.0 GB (134217727 MB)
23:10:57:547 (00010804) > [Startup] Avail virtual memory = 131068.7 GB (134214369 MB)
23:10:57:547 (00010804) > [Startup]
23:10:57:547 (00010804) > [NxApp] PreInit
23:10:57:547 (00010804) > [Steam] Initializing.
23:10:57:547 (00010804) > [Steam] Successfully initialized.
23:10:57:547 (00010804) > [SwapChain] Initializing...
23:10:57:547 (00010804) > [DXGI] Initializing...
23:10:57:547 (00010804) > [DXGI] Successfully initialized.
23:10:57:547 (00010804) > [Render] Enumerating adapters:
23:10:57:563 (00010804) > [Render] Adapter 0:
23:10:57:563 (00010804) > [Monitor] Description : AMD Radeon R7 200 Series
23:10:57:563 (00010804) > [Monitor] Vendor : AMD (1002)
23:10:57:563 (00010804) > [Monitor] Device : 6613
23:10:57:563 (00010804) > [Monitor] Sub system : e263174b
23:10:57:563 (00010804) > [Monitor] Revision : 0
23:10:57:563 (00010804) > [Monitor] Dedicated Video Memory : 2030 MB
23:10:57:563 (00010804) > [Monitor] Dedicated System Memory : 0000 MB
23:10:57:563 (00010804) > [Monitor] Shared System Memory : 4087 MB
23:10:57:563 (00010804) > [Monitor]
23:10:57:563 (00010804) > [Render] Loading ADL...
23:10:57:578 (00010804) > [Render] Done loading ADL and AGS
23:10:57:578 (00010804) > [Render] Adapter 1:
23:10:57:578 (00010804) > [Monitor] Description : AMD Radeon R7 200 Series
23:10:57:578 (00010804) > [Monitor] Vendor : AMD (1002)
23:10:57:578 (00010804) > [Monitor] Device : 6613
23:10:57:578 (00010804) > [Monitor] Sub system : e263174b
23:10:57:578 (00010804) > [Monitor] Revision : 0
23:10:57:578 (00010804) > [Monitor] Dedicated Video Memory : 2030 MB
23:10:57:578 (00010804) > [Monitor] Dedicated System Memory : 0000 MB
23:10:57:578 (00010804) > [Monitor] Shared System Memory : 4087 MB
23:10:57:578 (00010804) > [Monitor]
23:10:57:578 (00010804) > [Render] Adapter 2:
23:10:57:578 (00010804) > [Monitor] Description : Microsoft Basic Render Driver
23:10:57:578 (00010804) > [Monitor] Vendor : Unknown (1414)
23:10:57:578 (00010804) > [Monitor] Device : 8c
23:10:57:578 (00010804) > [Monitor] Sub system : 0
23:10:57:578 (00010804) > [Monitor] Revision : 0
23:10:57:578 (00010804) > [Monitor] Dedicated Video Memory : 0000 MB
23:10:57:578 (00010804) > [Monitor] Dedicated System Memory : 0000 MB
23:10:57:578 (00010804) > [Monitor] Shared System Memory : 4087 MB
23:10:57:578 (00010804) > [Monitor]
23:10:57:578 (00010804) > [Render] Enumerating monitors:
23:10:57:578 (00010804) > [Render] Monitor 0: handle = 0000000000010001, aspect = 1.60
23:10:57:578 (00010804) > [Render]
23:10:57:594 (00010804) > [Render] AMD Extension Version: 9.0

23:10:57:594 (00010804) > [Render] AMD HD3D Extension created.
23:10:57:594 (00010804) > [Render] AMD HD3D failed to initialize. (Most likely cause: there is no 3D support)
23:10:57:594 (00010804) > [Render] Enumerating Display Modes:
23:10:57:594 (00010804) > [Render] Querying ADL for Eyefinity modes
23:10:57:594 (00010804) > [Render] Monitor '1 (AMD Radeon R7 200 Series(1))' (0000000000010001):
23:10:57:594 (00010804) > [Render] - Mode 0 : 800 x 600 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 1 : 800 x 600 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 2 : 1024 x 768 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 3 : 1024 x 768 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 4 : 1152 x 864 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 5 : 1152 x 864 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 6 : 1280 x 720 @ 50 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 7 : 1280 x 720 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 8 : 1280 x 720 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 9 : 1280 x 768 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 10 : 1280 x 768 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 11 : 1280 x 800 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 12 : 1280 x 800 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 13 : 1280 x 960 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 14 : 1280 x 960 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 15 : 1280 x 1024 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 16 : 1280 x 1024 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 17 : 1360 x 768 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 18 : 1360 x 768 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 19 : 1366 x 768 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 20 : 1366 x 768 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 21 : 1440 x 900 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 22 : 1440 x 900 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render] - Mode 23 : 1680 x 1050 @ 60 Hz, stereo = 0
23:10:57:594 (00010804) > [Render]
23:10:57:594 (00010804) > [SwapChain] Successfully initialized.
23:10:57:594 (00010804) > [NxApp] PreInit successful.
23:10:57:609 (00010804) > [Main] Current directory: D:\JeuxSteam\steamapps\common\Rise of the Tomb Raider
23:10:57:609 (00010804) > [Main] Working directory: D:\JeuxSteam\steamapps\common\Rise of the Tomb Raider
23:10:57:609 (00010804) > [MultiCore] CPU count: logical = 4, cores = 2, physical = 1
23:10:57:735 (00010804) > [Main] Steam Language: '(null)'
23:10:57:735 (00010804) > [Main] Settings: Text Language: 'fr-fr' | VO Language: 'fr-fr' | Steam Game Language 'fr-fr'
23:10:57:735 (00010804) > [Main] Using: Text Language: 'fr-fr' | VO Language: 'fr-fr'
23:10:57:750 (00010804) > [Validate Settings] Desktop settings (Resolution: 1680 x 1050, Multi-monitor: off, Bezel correction: off)
23:10:59:141 (00010804) > [Validate Settings] Desktop settings (Resolution: 1680 x 1050, Multi-monitor: off, Bezel correction: off)
23:10:59:141 (00010804) > [D3D] Initializing...
23:10:59:141 (00010804) > [Render] AMD: Released AMD Extension.
23:10:59:141 (00010804) > [D3D] Loaded d3d11.dll
23:10:59:141 (00010804) > [D3D] Obtained D3D11CreateDevice address
23:10:59:141 (00010804) > [D3D] Successfully initialized
23:10:59:156 (00010804) > [D3D] Max supported feature level: 11.0
23:10:59:156 (00009716) > [D3D] Creating D3D Device...
23:10:59:156 (00009716) > [SwapChain] Creating D3D on adapter '1 (AMD Radeon R7 200 Series(1))'.
23:10:59:156 (00009716) > [SwapChain] Created D3D device with feature level 11.0.
23:10:59:156 (00009716) > [D3D] Successfully created.
23:10:59:156 (00010804) > [NxApp] Querying GPU Driver Info...
23:10:59:156 (00010804) > [NxApp] Enumerating available display adapters:
23:10:59:156 (00010804) > [NxApp] AMD Radeon R7 200 Series (active)
23:10:59:156 (00010804) > [NxApp] AMD Radeon R7 200 Series (active)
23:10:59:172 (00010804) > [NxApp] Successfully found GPU Driver Info
23:10:59:172 (00010804) > [NxApp] Driver Desc: AMD Radeon R7 200 Series
23:10:59:172 (00010804) > [NxApp] Driver Version: 15.301.1801.1001
23:10:59:172 (00010804) > [Settings] DirectX Version: 11
23:10:59:172 (00010804) > [Settings] Window mode:
23:10:59:172 (00010804) > [Settings] Fullscreen: 1
23:10:59:172 (00010804) > [Settings] Excl.Fullscreen: 1

23:10:59:172 (00010804) > [Settings] Monitor: 0
23:10:59:172 (00010804) > [Settings] Monitor Rect: x: 0 y: 0 w: 1680 h: 1050
23:10:59:172 (00010804) > [Settings] Workspace Rect: x: 0 y: 0 w: 1680 h: 1010
23:10:59:172 (00010804) > [Settings] Aspect Ratio: 1.597786 (Pixel Aspect Ratio: 1.001386)
23:10:59:172 (00010804) > [Settings] Fullscreen display mode:
23:10:59:172 (00010804) > [Settings] Display mode: 1440x900@60
23:10:59:172 (00010804) > [Settings] VSync: 1, TripleBuffer: 0
23:10:59:172 (00010804) > [Settings] MultiMonitor: 0
23:10:59:172 (00010804) > [Settings] BezelCorrected: 0
23:10:59:172 (00010804) > [Settings] Stereoscopic3D: 0
23:10:59:172 (00010804) > [Settings] Window settings:
23:10:59:172 (00010804) > [Settings] Window rect: x: 210 y: 171 w: 1260 h: 708
23:10:59:172 (00010804) > [Settings] User window: w: 1260 h: 708
23:10:59:172 (00010804) > [Settings] Window maximized: 0
23:10:59:172 (00010804) > [Settings] Graphics Options:
23:10:59:172 (00010804) > [Settings] TextureQuality: 1, TextureFiltering: 1, ShadowQuality: 1
23:10:59:172 (00010804) > [Settings] AO: 1, DOF: 1, FXAA: 1, SMAA: 0, SSAA: 0, Bloom: 1
23:10:59:172 (00010804) > [Settings] Motijava-script: 1 VignetteBlur: 1 Tessellation: 1
23:10:59:172 (00010804) > [Settings] LensFlares: 1 ScreenFX: 1 SSR: 1 HairQuality: 0
23:10:59:172 (00010804) > [Settings] Specular Reflection Quality: 0
23:10:59:172 (00010804) > [Settings] FoliageQuality: 1
23:10:59:172 (00010804) > [Settings] FOVCorrection :1.000000
23:10:59:172 (00010804) > [Settings] LevelOfDetail: 1
23:10:59:172 (00010804) > [Settings] StereoSeparation: 0.110000
23:10:59:172 (00010804) > [Settings] StereoFarNear: 5.000000
23:10:59:172 (00010804) > [Settings] StereoNearSeparationMultiplier :0.350000
23:10:59:172 (00010804) > [NxApp] Creating window...
23:10:59:172 (00004920) > [Input] Keyboard language: "Français (France)" (id: 1036)
23:10:59:172 (00004920) > [Input] Keyboard physical layout: "French" (id: 0000040C)
23:10:59:172 (00004920) > [Input] Mouse "Logitech HID-compliant Unifying Mouse" id 256 buttons 16 sampleRate 0 horizontalWheel no
23:10:59:172 (00004920) > [Input] Keyboard "Logitech HID-compliant Unifying keyboard" type 81 subType 0 mode 1 function 12 indicators 3 total 173
23:10:59:172 (00004920) > [Input] Joystick "" product 50475 vendor 1133 version 4609 usage 1 usagePage 12 xinput no
23:10:59:172 (00004920) > [Input] Joystick "" product 50475 vendor 1133 version 4609 usage 2 usagePage 65280 xinput no
23:10:59:172 (00004920) > [Input] Joystick "" product 50475 vendor 1133 version 4609 usage 1 usagePage 65280 xinput no
23:10:59:172 (00004920) > [Input] Mouse "HID-compliant mouse" id 256 buttons 16 sampleRate 0 horizontalWheel no
23:10:59:172 (00004920) > [Input] Keyboard "HID Keyboard Device" type 81 subType 0 mode 1 function 12 indicators 3 total 173
23:10:59:172 (00004920) > [Input] Joystick "" product 50475 vendor 1133 version 4609 usage 136 usagePage 65468 xinput no
23:10:59:172 (00004920) > [Input] Joystick "" product 50475 vendor 1133 version 4609 usage 1 usagePage 12 xinput no
23:10:59:172 (00004920) > [Input] Mouse "HID-compliant mouse" id 256 buttons 8 sampleRate 0 horizontalWheel no
23:10:59:172 (00004920) > [Input] Keyboard "HID Keyboard Device" type 81 subType 0 mode 1 function 12 indicators 3 total 240
23:10:59:172 (00004920) > [Input] Joystick "" product 50444 vendor 1133 version 8768 usage 2 usagePage 65280 xinput no
23:10:59:172 (00004920) > [Input] Joystick "" product 50487 vendor 1133 version 13312 usage 128 usagePage 65408 xinput no
23:10:59:172 (00004920) > [Input] Joystick "" product 50487 vendor 1133 version 13312 usage 2 usagePage 65280 xinput no
23:10:59:172 (00004920) > [Input] Joystick "" product 50487 vendor 1133 version 13312 usage 1 usagePage 65280 xinput no
23:10:59:172 (00004920) > [Input] Joystick "" product 50444 vendor 1133 version 8768 usage 1 usagePage 65280 xinput no
23:10:59:172 (00004920) > [Input] Joystick "" product 50487 vendor 1133 version 13312 usage 1 usagePage 12 xinput no
23:10:59:172 (00004920) > [Input] Joystick "" product 50444 vendor 1133 version 8768 usage 1 usagePage 12 xinput no
23:10:59:172 (00004920) > [Input] Keyboard "Logitech HID-Compliant Keyboard" type 81 subType 0 mode 1 function 12 indicators 3 total 173
23:10:59:172 (00004920) > [Input] Keyboard "HID Keyboard Device" type 81 subType 0 mode 1 function 12 indicators 3 total 264
23:10:59:172 (00004920) > [Input] Mouse "Logitech Cordless Gaming Receiver" id 256 buttons 16 sampleRate 0 horizontalWheel no
23:10:59:172 (00004920) > [Input] Mouse "Logitech HID-compliant Cordless Mouse" id 256 buttons 8 sampleRate 0 horizontalWheel no
23:10:59:172 (00010804) > [NxApp] Window created.
23:10:59:172 (00010804) > [NxApp] Initializing swapchain...
23:10:59:172 (00009716) > [SwapChain] Creating...
23:10:59:172 (00009716) > [Render] AMD Extension Version: 9.0

23:10:59:172 (00009716) > [Render] AMD HD3D Extension created.
23:10:59:172 (00009716) > [Render] AMD HD3D failed to initialize. (Most likely cause: there is no 3D support)
23:10:59:172 (00009716) > [DXGI] Created swapchain.
23:10:59:563 (00009716) > [DXGI] Set-up exclusive fullscreen
23:10:59:563 (00009716) > [SwapChain] Gamma correction is enabled.
23:10:59:563 (00009716) > [SwapChain] Successfully created.
23:10:59:594 (00010804) > [NxApp] Swapchain initialized
23:10:59:594 (00010804) > [NxApp] Initializing renderer...
23:10:59:594 (00010804) > [NxApp] Renderer initialized
23:10:59:594 (00010804) > [Render] CROSSFIRE GPU count query failed, no multi-gpu optimizations.
23:10:59:594 (00010804) > [Main] Starting Tomb Raider v1.0 build 616.5_64
23:10:59:609 (00010804) > [D3D] [Render] PCDX11DeviceManager constructor start
23:10:59:609 (00010804) > [D3D] D3D Adapter Information:
23:10:59:609 (00010804) > [D3D] Adapter Description: AMD Radeon R7 200 Series
23:10:59:609 (00010804) > [D3D] VendorID: 1002
23:10:59:609 (00010804) > [D3D] DeviceID: 6613
23:10:59:609 (00010804) > [D3D] Revision: 0
23:10:59:609 (00010804) > [D3D]
ATIAGSGetDefaultDisplayIndex says 0.

23:10:59:609 (00010804) > [D3D] CROSSFIRE GPU count 1.

23:10:59:656 (00010804) > [HBAO+] HBAO+ Context creation succeeded
23:10:59:703 (00010804) > [D3D] D3D Adapter Information:
23:10:59:703 (00010804) > [D3D] Adapter Description: AMD Radeon R7 200 Series
23:10:59:703 (00010804) > [D3D] VendorID: 1002
23:10:59:703 (00010804) > [D3D] DeviceID: 6613
23:10:59:703 (00010804) > [D3D] Revision: 0
23:10:59:703 (00010804) > [D3D]
ATIAGSGetDefaultDisplayIndex says 0.

23:10:59:703 (00010804) > [D3D] CROSSFIRE GPU count 1.

23:10:59:719 (00010804) > [HBAO+] HBAO+ Context creation succeeded
23:10:59:719 (00010804) > [D3D] [Render] Adapter A has no outputs!
23:10:59:719 (00010804) > [D3D] D3D Adapter Information:
23:10:59:719 (00010804) > [D3D] Adapter Description: Microsoft Basic Render Driver
23:10:59:719 (00010804) > [D3D] VendorID: 1414
23:10:59:719 (00010804) > [D3D] DeviceID: 8c
23:10:59:719 (00010804) > [D3D] Revision: 0
23:10:59:719 (00010804) > [HBAO+] HBAO+ Context creation succeeded
23:10:59:734 (00010804) > [D3D] [Render] Adapter M has no outputs!
23:10:59:734 (00010804) > [D3D] [Render] PCDX11DeviceManager constructor end
23:10:59:734 (00010804) > [D3D] D3D Adapter Information:
23:10:59:734 (00010804) > [D3D] Adapter Description: AMD Radeon R7 200 Series
23:10:59:734 (00010804) > [D3D] VendorID: 1002
23:10:59:734 (00010804) > [D3D] DeviceID: 6613
23:10:59:734 (00010804) > [D3D] Revision: 0
23:10:59:734 (00010804) > [D3D]
ATIAGSGetDefaultDisplayIndex says 0.

23:10:59:734 (00010804) > [D3D] CROSSFIRE GPU count 1.

23:10:59:750 (00010804) > [HBAO+] HBAO+ Context creation succeeded
23:11:00:297 (00010804) > [Sound] Initalizing audio...
23:11:00:469 (00010804) > [Sound] Audio device found. FMOD reports 2 driver(s).
23:11:00:469 (00010804) > [Sound] Audio Driver Name: Haut-parleurs (Realtek High Definition Audio)
23:11:00:469 (00010804) > [Sound] Speaker Mode: 2
23:11:01:875 (00010804) > [Input] Assigned gamepad -1 to player 0
23:11:03:170 (00006036) > [Settings] New display settings are:
23:11:03:170 (00006036) > [Settings] DirectX Version: 11
23:11:03:170 (00006036) > [Settings] Window mode:
23:11:03:170 (00006036) > [Settings] Fullscreen: 1
23:11:03:170 (00006036) > [Settings] Excl.Fullscreen: 1
23:11:03:170 (00006036) > [Settings] Monitor: 0
23:11:03:170 (00006036) > [Settings] Monitor Rect: x: 0 y: 0 w: 1680 h: 1050
23:11:03:170 (00006036) > [Settings] Workspace Rect: x: 0 y: 0 w: 1680 h: 1010
23:11:03:170 (00006036) > [Settings] Aspect Ratio: 1.597786 (Pixel Aspect Ratio: 1.001386)
23:11:03:170 (00006036) > [Settings] Fullscreen display mode:
23:11:03:170 (00006036) > [Settings] Display mode: 1440x900@60
23:11:03:170 (00006036) > [Settings] VSync: 1, TripleBuffer: 0
23:11:03:170 (00006036) > [Settings] MultiMonitor: 0
23:11:03:170 (00006036) > [Settings] BezelCorrected: 0
23:11:03:170 (00006036) > [Settings] Stereoscopic3D: 0
23:11:03:170 (00006036) > [Settings] Window settings:
23:11:03:170 (00006036) > [Settings] Window rect: x: 210 y: 171 w: 1260 h: 708
23:11:03:170 (00006036) > [Settings] User window: w: 1260 h: 708
23:11:03:170 (00006036) > [Settings] Window maximized: 0
23:11:03:170 (00006036) > [Settings] Graphics Options:
23:11:03:170 (00006036) > [Settings] TextureQuality: 1, TextureFiltering: 1, ShadowQuality: 1
23:11:03:170 (00006036) > [Settings] AO: 1, DOF: 1, FXAA: 1, SMAA: 0, SSAA: 0, Bloom: 1
23:11:03:170 (00006036) > [Settings] Motijava-script: 1 VignetteBlur: 1 Tessellation: 1
23:11:03:170 (00006036) > [Settings] LensFlares: 1 ScreenFX: 1 SSR: 1 HairQuality: 0
23:11:03:170 (00006036) > [Settings] Specular Reflection Quality: 0
23:11:03:170 (00006036) > [Settings] FoliageQuality: 1
23:11:03:170 (00006036) > [Settings] FOVCorrection :1.000000
23:11:03:170 (00006036) > [Settings] LevelOfDetail: 1
23:11:03:170 (00006036) > [Settings] StereoSeparation: 0.110000
23:11:03:170 (00006036) > [Settings] StereoFarNear: 5.000000
23:11:03:170 (00006036) > [Settings] StereoNearSeparationMultiplier :0.350000
23:11:03:170 (00006036) > [Settings] End of settings.
23:11:03:170 (00006036) > [Render] CROSSFIRE GPU count query failed, no multi-gpu optimizations.
23:11:03:170 (00006036) > [NxApp (Render Thread)] Finished enforcing display settings
23:11:03:170 (00010804) > [NxApp] Finished enforcing display settings
23:11:08:492 (00010804) > [Menu] UiMenuStateSquareEnixMembers::OnEnter: bFromStartupFlow=1, HasSEMBeenHandled=1, bIsOnline=1


My crossfire work or not work???? For me: NO

Files integrity checked by steam: OK.
AMD Drivers (optimized for ROTTR) installed and ROTTR AMD profile active.